Transplantation, Therapy and Nutrigenomics

Use of stem cells for transplantation is over 4 decades old. In India it began in the first decade of this millennium. The procedure was limited to the use of Bone Marrow as the preferred source till a few years ago and was better recognised as “BMT” or Bone Marrow Transplant.

In recent times, use of peripheral blood with mobilisation and apheresis process has become more prevalent as a sample for harvesting stem cells for transplant. Use of peripheral blood is less invasive and equally effective to source the relevant cell type for an effective transplant. The process is, therefore, is now referred to as Hematopoietic Stem Cell Transplant (HSCT). HEMATO HSCT

HSCT procedure can be initiated with patient him/herself as the source for stem cells and is called Autologous Stem Cell Transplant. It can also be undertaken with HLA matched Donor sample and is called Allogeneic Stem Cell Transplant. Allogeneic procedure where the donor is a 50% match, mostly, a parent for the child or one of the children for parents or even siblings and at times a totally unrelated donor, is better known as Haploidentical Stem cell Transplant.

Considering the lack of 100% or near 100% matched donors, and easier availability of Haploidentical Donors, there is a marked increase in Haploidentical Stem Cell Transplants globally. In India too, while Haploidentical was more prevalent in pediatric categories, it is fast becoming the norm even among adults.

Considering the lack of 100% or near 100% matched donors, and easier availability of Haploidentical Donors, there is a marked increase in Haploidentical Stem Cell Transplants globally. In India too, while Haploidentical was more prevalent in pediatric categories, it is fast becoming the norm even among adults.

Stem Cell Therapies using MSCs are showing huge promise as an effective way forward for Regenerative Medicine and Personalized treatments. MSCs are also the preferred mode of use in 1000s of clinical trials globally for treating a host of medical conditions related to nearly all aspects, organs and systems of the human body. These include heart, neuro, ortho, gynae, musculoskeletal, tumours, gastrointestinal, brain, lifestyle and chronic ailments – diabetes and much more.

Use of stem cells for preventive and curative procedures will continue to rise as researchers and scientists find more and better results based on their continued studies and clinical trials about the regenerative and differentiative capabilities of these cells. Medical Advancements

It is, therefore, a highly advisable step for all of us to opt for CRYOstorage of our Healthy Stem Cells for long period including up to 10 years. A Trusted CRYOstorage facility with Controlled Rate Freezing and advanced clinical procedures to ensure > 90% vitality of the stem cells for use, when required, under Vapour Liquid Nitrogen environment maintained at -196 o C can be a life saver. HEMATOCRYO

The recent pandemic took away many and resulted in quite a few being hospitalized including those who were “outwardly” physically fit and having a good healthy life. There genetic anomalies would definitely have a significant role to play in their respective conditions. HEMATO PREGEN

A well proven and scientifically accepted fact is the impact of our diet, environment and living conditions on the way our genes will respond. Consequently, even among identical twins, phenotype, or the set of observational characteristics of each of them resulting from the interaction of their respective genotype with environment, is different. A significant reason is the interaction of nutrition we take daily with the genes within us.

NUTRIGENOMICs is the scientific study of the interaction of nutrition and genes, in particular for the prevention or treatment of diseases resulting rom genetic anomalies. Understanding of Nutrigenomics is highly recommended for everyone indulging in customized diets and those opting for a regiment of exercise going beyond the normal. It is essential to understand the genetic anomalies and their impact on our healthy before indulging in the modern-day diet options such as Keto…or integrated exercises which may result in a toned body or rapid weight loss but also lead to irreversible medical conditions triggering the underlying genetic anomalies to become active. HEMATO PREGEN